CRISPR makes cancer cells turncoats that attack their tumor, mouse study finds

first_img [email protected] By Sharon Begley July 11, 2018 Reprints In the LabCRISPR makes cancer cells turncoats that attack their tumor, mouse study finds As an idea for wiping out cancer, it could have been ripped from the pages of a spy thriller: Take cancer cells that have departed the original tumor and spread elsewhere in the body, genome-edit them to be stone-cold killers, then wait for the homesick cells to return and make like émigré assassins.In a study four years in the making, scientists reported on Wednesday that “rehoming” cells that had been CRISPR’d to attack cells in the original tumor improved survival in lab mice with brain cancer, as well as in mice with breast cancer that spread to the brain.That cancer cells migrate back to the original tumor after metastasizing to distant sites is still, 12 years after its discovery, one of the most unexpected and perplexing in cancer biology. Called self-seeding or (redundantly) rehoming, the surprising behavior has inspired several treatment ideas, such as putting cancer-cell-killing viruses or suicide genes into the rehoming cells (which would somehow have to be made resistant to those lethal agents) and hoping they transfer their lethal payload to the tumor cells they find when they return home.advertisement Please enter a valid email address. Leave this field empty if you’re human: Biologist Khalid Shah, director of the Center for Stem Cell Therapeutics and Imaging at Brigham and Women’s Hospital and the leader of the study, said he’s not deterred by the challenge. Since rehoming tumor cells “can track the original tumors, it is a matter of taming these cells to find the ultimate cure,” he said.advertisement Privacy Policy He’s planning a startup company to turn rehoming cells into cancer killers, Shah said, adding that in the year since the new study was submitted to the journal, he and his colleagues have obtained more data on how well CRISPR’d rehoming tumor cells can attack cancer: “We’re in it for the long term.”Other scientists who have investigated rehoming cancer cells said they can imagine a therapy based on these returning émigrés looking promising enough to enter clinical trials. “With sufficient resources and sophisticated expertise, one could see this being developed toward a Phase 1 trial,” said cancer biologist Renata Pasqualini of Rutgers University. She led a 2016 study that used rehoming cancer cells to deliver an anti-tumor compound directly to primary and metastatic tumors in mice; that reduced the tumors’ growth, damaged the blood vessels they need to survive, and triggered a self-destruct mechanism in many of the cells. The chance of her approach or Shah’s being tested in people, she cautioned, “really depends on safety being demonstrated.”For their new study, Shah and his colleagues first removed tumor cells from mice. (If the approach ever makes it to patients, isolating cells from a biopsy or from a surgically removed tumor would also be the first step.) They then used the genome-editing technology CRISPR to make the tumor cells express a molecule that activates the aptly named “death receptor” on cancer cells, causing the cells to self-destruct. Any genome-editing technology would probably work, Shah said, but CRISPR is the easiest. Most of those approaches have stumbled, and the new study, published in Science Translational Medicine, is very preliminary and comes with the usual caveats. If experimental cancer therapies worked as well in people as they do in lab mice, the War on Cancer would have been won years ago. Instead, the chance that an experimental cancer therapy will become an approved therapy is about 5 percent. And that’s of the ones that enter clinical trials. Many treatment ideas fail even earlier. Injected into mice, the cells made their way to all three types of tumors the scientists tested: primary glioblastoma, the most lethal form of brain cancer; recurrent glioblastoma, in which the cancer was treated but returned because it became resistant to the standard chemotherapy; and breast cancer that had metastasized to the brain. The rehoming cells brought “marked survival benefits,” the scientists wrote.In mice with primary or recurring brain cancer, tumors shrank considerably and 90 percent of the rodents survived for weeks or months after treatment, Shah said; usually such glioblastomas are nearly 100 percent fatal in both mice and people, and were so in untreated mice in the experiment. In mice with the brain metastases, about half survived for several weeks after the cell therapy — evidence that engineered rehoming tumor cells might be therapeutic.A key unanswered question is what happens to distant metastases even if CRISPR’d rehoming cells successfully attack the original tumor. As far as biologists know, they make a one-way trip, to the primary tumor but not to distant metastases, which can occur in multiple organs. Those metastases, not the original tumor, are responsible for upwards of 90 percent of cancer deaths. Another question is how to keep CRISPR’d rehoming cells from going rogue and initiating new tumors rather than killing the original one; CRISPR’d or not, they’re still cancer cells.Shah and his team gave the engineered cells a kill switch so that administering a simple drug would kill them, presumably after they had eliminated cancer cells and before they had seeded any new tumors. It remains to be seen how well that would work in people. STAT+: Exclusive analysis of biopharma, health policy, and the life sciences. @sxbegle About the Author Reprints Sharon Begley Senior Writer, Science and Discovery (1956-2021) Sharon covered science and discovery. Tags cancerCRISPRresearch Newsletters Sign up for Cancer Briefing A weekly look at the latest in cancer research, treatment, and patient care. CRISPR’ed cancer cells (green) shown returning to the original glioblastoma tumor (red) in a mouse brain. Courtesy BWHlast_img read more

Lab strips James Watson of final honorary roles after his continuing racist statements

first_imgIn the LabLab strips James Watson of final honorary roles after his continuing racist statements Scientific luminaries threw James Watson a birthday party weeks before Eric Lander’s widely criticized toast Sharon Begley “I believe there is very broad support among the faculty for the multiple steps that CSHL is taking in response to Watson’s horrific comments,” CSHL biologist Justin Kinney, who has been a vocal critic of those comments, told STAT. “The CSHL administration has been very proactive on this matter, seeking input from all of us as well as from many members of the broader scientific community.” The director of the documentary, which aired last week as part of the PBS “American Masters” series, asked Watson if he had changed his mind about his previous statements and writings on race and intelligence, which boil down to the claim that Africans and people of African descent have lower intelligence than other groups because of genetics. Watson declined that lifeline. Stillman’s and Simons’ statement added that the lab “acknowledges and appreciates Dr. Watson’s substantial scientific legacy, including his role as founding director of the Human Genome Project.”Watson, 90, was seriously injured in a car accident last year, and since then had been hospitalized for several weeks and then admitted to a skilled nursing facility. Asked whether Watson or his family had been informed of the actions ahead of time, lab spokeswoman Dagnia Zeidlickis did not reply directly, but said there were “no surprises for anyone.” The lab that James Watson led for decades has stripped the Nobel laureate of his last remaining honorary positions, it announced on Friday, in reaction to Watson’s refusal (in a recent documentary) to take back statements widely regarded as racist.In a statement, Cold Spring Harbor Laboratory’s CEO Bruce Stillman and the chair of its board of trustees Marilyn Simons said the lab “unequivocally rejects the unsubstantiated and reckless personal opinions Dr. James D. Watson expressed on the subject of ethnicity and genetics” in the PBS documentary. The statements “are reprehensible, unsupported by science, and in no way represent the views of CSHL, its trustees, faculty, staff, or students. The Laboratory condemns the misuse of science to justify prejudice.”It added that the statements “are completely and utterly incompatible with our mission, values, and policies, and require the severing of any remaining vestiges of his involvement” in the lab.advertisement By Sharon Begley Jan. 11, 2019 Reprints When Watson, co-discoverer with Francis Crick of DNA’s double helix structure, first made the offensive (and scientifically baseless) statements in 2007, CSHL, which Watson had saved from ruin and built into a leader in biological research, took away his administrative duties and rescinded his status as chancellor. In its latest step, it revoked his honorary titles of chancellor emeritus, Oliver R. Grace Professor Emeritus, and honorary trustee. It did so, the statement said, because Watson’s remarks in the documentary, which was filmed from 2016 to 2018, “effectively reverse the written apology and retraction Dr. Watson made in 2007,” when he expressed remorse for his racist assertions.advertisement James Watson speaking at the Russian Academy of Sciences in Moscow in 2015. Ivan Sekretarev/APcenter_img Tags ethicsgeneticsresearch Related: Related: [email protected] ‘I really don’t know what happened to Jim’: Friends ask where James Watson’s odious attitudes about race came from About the Author Reprints @sxbegle Senior Writer, Science and Discovery (1956-2021) Sharon covered science and discovery.last_img read more

Laois man fondly remembered as a teacher, performer and footballer

first_img Facebook Pinterest Laois man fondly remembered as a teacher, performer and footballer GAA His funeral will be arriving Church of The Assumption, The Heath on Sunday, December 15 for 12 noon Requiem Mass. Burial after in the adjoining cemetery.Family time on Sunday morning please.SEE ALSO – Tributes paid as well-known Laois GAA administrator set to leave roleSEE ALSO – Have you got your Christmas stocking fillers – check out the Laois Today store 2020 U-15 ‘B’ glory for Ballyroan-Abbey following six point win over Killeshin Here are all of Wednesday’s Laois GAA results Twitter Kelly and Farrell lead the way as St Joseph’s claim 2020 U-15 glory TAGSRichard BoothThe Heath RELATED ARTICLESMORE FROM AUTHOR Pinterestcenter_img WhatsApp WhatsApp Twitter Home News Community Laois man fondly remembered as a teacher, performer and footballer NewsCommunity Facebook GAA GAA Previous articleRange of products for sale in Frankie’s Hairdressing in Mountmellick this ChristmasNext articleWith Bruno McCormack now retired, here’s 20 of the best left boots in Laois John WhelanJohn Whelan has been a journalist, commentator, columnist, political analyst, campaigner, politician and publisher ever since he was 17. Having been Editor of the Leinster Express, Offaly Express and the Leinster Leader he has also contributed extensively on a number of issues to all of the country’s flagship titles and programmes including the Irish Press, The Irish Independent, the Star, the Sunday Independent, the Sunday Business Post, The Sunday Times and Prime Time. He is founder of Communicate Ireland a PR, public affairs, event management and media services company.He is the author of the popular camping blog, Vanhalla – Camper Heaven. By John Whelan – 13th December 2019 Members of the Laois Musical Society performing at their production of Carousel in The Dunamaise Theatre, Portlaoise in the year 2000, with Richard Booth as “Enoch Snow” having a word with Yvonne Murphy as “Carrie Pipperidge”. The death has taken place of Richard Booth of Killeen, Mountmellick.Popularly and affectionately known as ‘Blondie’ Richard he was a retired Deputy Principal of St Paul’s School on the Borris Road.He kicked football with the Heath and also lined out for the county. He won a senior title with the Heath in 1974 when he togged out at half-back. The Heath beat their neighbours Emo that day, after a replay.He was also a highly regarded and gifted performer who played major roles in the productions of both the Laois Musical Society and the Portlaoise Panto. Colleagues and friends speak of him in glowing terms as a true gent.Richard was the beloved son of the late Joe and Emma Booth, Ballyduff, Stradbally.He is deeply regretted by his loving wife Norma and his family Shane, Ciara and Fiona, granddaughter Chloe, brothers and sisters, uncle Paddy, aunt Ter, nephews, nieces, father-in-law Jack Hedigan (Clonakilty), son-in-law Ray, brothers-in-law, sisters-in-law, neighbours, relatives and a large circle of friends.Reposing in Moloney’s Funeral Home, Mountmellick today, Friday, December 13 from 5pm (R32PC95). There will be recital of the Rosary at 8pm.Also reposing at his home (R32V8C0) on Saturday from 3.30pm. Recital of the Rosary at 8.30pm.last_img read more

Fred Durst expresses love for station wagons all over Instagram

first_img We encourage all readers to share their views on our articles using Facebook commenting Visit our FAQ page for more information. RELATED TAGSNews See More Videos What “priceless” advice could a station wagon possibly provide? How to remain generally unchanged for decades? Based on the captions one can assume he has either named the different vehicles in his posts or he is keeping track of the days of the week. We may never know.https://www.instagram.com/p/BaSKSADHno1/?taken-by=freddursthttps://www.instagram.com/p/BaMjk_AHyM3/?taken-by=freddursthttps://www.instagram.com/p/BaJ6m5PHDLw/?taken-by=freddursthttps://www.instagram.com/p/BZ9HeIRnR28/?taken-by=freddurstFurthermore, it seems Durst has developed quite the bond with his subjects.https://www.instagram.com/p/BhxsbZfnD1Q/?taken-by=freddurst center_img COMMENTSSHARE YOUR THOUGHTS Trending Videos Fred Durst is still rollin’ as the lead singer of Limp Bizkit, and in addition to sharing his love for music with the world, he has taken to expressing his passion for an unlikely subject on social media.The controversial rock and hip-hop star of the late-’90s-through-early-2000s has an Instagram account full of station wagons, and a Twitter account that attempts to send his loyal following to his eclectic collection.Yes, you read that right. last_img read more

Aerospace Companies To Test CU's Citizen Explorer Satellite

first_imgShare Share via TwitterShare via FacebookShare via LinkedInShare via E-mail Published: Aug. 16, 2000 Note to Editors: Print and broadcast media planning on covering either event should contact Chris Koehler or Jim Scott at least one day in advance of testing.Two Denver-Boulder area aerospace companies will contribute their time and expertise to test a NASA satellite designed and built by students at the University of Colorado at Boulder during August in anticipation of a November 2000 launch.Engineers at Lockheed Martin Astronautics of Denver will conduct a full day of tests on the properties of the educational satellite on Aug. 28, said Colorado Space Grant College Deputy Director Chris Koehler. The team of Lockheed Martin engineers have offered their assistance and access to the company’s testing facilities free of charge for the Citizen Explorer Satellite, designed and built by CU-Boulder students at the campus-headquartered CSGC. The Lockheed Martin engineers will test the mass properties of the satellite using a special “spin-table,” said Koehler. “We need to determine what the center of gravity and moments of the satellite’s inertia will be in order to effectively control the spacecraft,” he said. “The findings of this particular test will be used to help us predict how the satellite will physically interact with the launch vehicle.”The Earth-orbiting Citizen Explorer will measure atmospheric ozone and solar ultraviolet radiation as part of a larger educational effort that will involve thousands of K-12 students around the world. The 100-pound satellite is slated for launch aboard a Delta 2 rocket from Vandenburg Air Force Base in California free of charge as a secondary “piggyback” payload through a joint effort by NASA and the Boeing Co.Ball Aerospace and Technologies Corp. of Boulder also will conduct a series of tests on Citizen Explorer beginning Aug. 21. They include a vibration test on a special “shake-table” to assess the structural integrity of the satellite, assuring the craft can withstand the physical stresses during launch and orbit, Koehler said. Ball also will test the electromagnetic interference the satellite’s electrical system emits. “This electromagnetic interference limits our ability to understand the parameters of the magnetic field surrounding the spacecraft, which is crucial for effective navigation of the satellite,” said aerospace engineering senior Kyran Owen-Mankovich, program manager for the Citizen Explorer project. In addition, Ball will conduct a thermal vacuum test to assess how the Citizen Explorer will behave under extreme temperatures. “It’s corporations in our community like Lockheed Martin and Ball that are willing to provide resources when necessary for the students to complete their projects leading toward the launch of the spacecraft,” said Koehler.The satellite will be placed in a circular orbit 440 miles above the Earth, allowing it to pass over the planet at 10 a.m. local time each day. The satellite will directly downlink data to receivers at participating schools worldwide, which will gather science data and evaluate global and regional ozone concentrations on a computer network.Schools that purchase receiver antennas will become satellite ground stations for the effort and have the ability to monitor the systems of Citizen Explorer and to track its orbit. This information will then be sent to the student satellite operators at the CSGC mission control center at the CU-Boulder College of Engineering and Applied Science. “This project is going to be an educational experience on various levels,” said Owen-Mankovitch. “It has provided me and many other students with an amazing opportunity, and we are taking the project to a whole new level by allowing K-12 students from all over the world to participate in an exciting study that pertains to them in a very direct way.”The CSGC consortium, which includes 17 Colorado colleges, universities and institutions, has developed workshops that will help teachers and students to better understand basic principles surrounding satellites and environmental issues such as ozone depletion and UV radiation. “These workshops will help the program develop a strong independent structure,” said Owen-Mankovitch. “We want the schools involved in the project to be able to participate in a self-sufficient manner.”last_img read more

10 things to do this week: Jan. 29 edition

first_imgShare Share via TwitterShare via FacebookShare via LinkedInShare via E-mail Published: Jan. 29, 2018 This week brings Tuesday Morning Coffee for entrepreneurially minded students, drop-in academic skills coaching, movies playing on campus, free injury screening, the chance to apply for leadership scholarships and the Journey Leader team, the 15th annual Poetry Slam, a free live talk about asteroids and more, and a BFA dance concert. Find more campus events with the new and improved Events Calendar.Tuesday, Jan. 30Silicon Flatirons Tuesday Morning CoffeeTuesday Morning Coffee is an opportunity for entrepreneurially minded students on campus to meet peers and leaders from the Front Range’s active entrepreneurship scene. Whether you’re already an entrepreneur or interested in learning more, there’s a mug ready for you. Stop by the Idea Forge from 7:45 to 8:45 a.m. Light breakfast will be provided. Seating is limited, so register now! Drop-in academic skills coachingStop by the Fleming Building, room 190, from 2 to 3:30 p.m. and start to improve your studying skills. Come with questions or concerns, and the Student Academic Success Center can help map out a plan for any class or other challenge.Program Council Film Series: Blade Runner 2049Come check out the long anticipated sequel to one of the best loved sci-fi films of all time. Harrison Ford and Ryan Gosling star. As always, there will be free popcorn. Showing from 8 to 11 p.m. in Chem 140.Wednesday, Jan. 31Free injury screeningThe Musculoskeletal Injury “MSK” clinic provides free screenings for minor injuries involving muscles and joints by a physical therapist. Recommendations for injury prevention and self-care are also provided. Stop by the Rec Center and Wardenburg Health Center during walk-in hours.Apply for $1,000 leadership scholarshipIf you’re currently involved in a CUSG-recognized student group, or work as a student staff member in the UMC, then you are eligible to apply for a $1,000 scholarship (James E. Schafer Leadership Scholarship or Carlos García UMC Director’s Scholarship). Applications are due in UMC 305 by 4:30 p.m. on Monday, Feb. 26.Thursday, Feb. 1Poetry SlamJoin the Center for Student Involvement for the 15th annual Poetry Slam! Come experience the power of the spoken word delivered by CU Boulder poets. The event is free and open to all. Doors open at 7 p.m.; show starts at 7:30 p.m. in Old Main.Lead like Ralphie and become a Journey LeaderAre you proud to be a CU Buff? Do you want to gain valuable leadership experience? Then be the first to welcome new students and families to campus by joining the Journey Leader team! Learn more and apply today.“Solar System Leftovers: Asteroids, Comets, Rings, and Dwarfs”Swing by Fiske Planetarium at 7 p.m. for a free live talk and increase your knowledge tenfold about asteroids, comets, rings and dwarfs. Where did these distant rocks come from, and what dangers and mysteries could they hold for life here on Earth? Bring your Buff OneCard for entry.Friday, Feb. 2Friday Night Film Series – Thor: RagnarokDon’t miss the next installment in the Marvel Cinematic Universe. Chris Hemsworth, Tom Hiddleston and Kate Blanchett star in the third Thor film. Showing from 8 to 11 p.m. in Chem 140.Catapult: A BFA dance concertFour emerging BFA choreographers use original dance to share their knowledge of archetypes, science, philosophy and the natural world. Starts 7:30 p.m. in the Charlotte York Irey Theatre. Tickets are $16.Categories:Things to DoGeneralCampus CommunityEvents & Exhibitslast_img read more

Provost announces search committee for new law dean

first_imgShare Share via TwitterShare via FacebookShare via LinkedInShare via E-mail Published: Oct. 9, 2020 CU Boulder Provost Russell Moore has named the members of the committee to conduct a national search for a new dean for the University of Colorado Law School to succeed outgoing dean James Anaya.“The next dean will need to build on Jim’s outstanding achievements and his advancements in making Colorado Law more diverse, inclusive and accessible for students from a wide variety of backgrounds,” Moore said.Moore has named Michele Moses, vice provost and associate vice chancellor for faculty affairs, to head the search committee, which will create a leadership profile that will guide them in identifying candidates of the highest caliber. The committee will begin meeting on Oct. 9. Other members of the search committee include Colorado Law faculty, students and staff, as well as representatives from the community who are also alumni, and a representative of the university’s Advancement team.Members of the search committee for the new Colorado Law dean are:Amy Bauer, senior instructor and co-director of the Master of Studies in Law Ethics & Compliance program.Frederic Bloom, professor of law and associate dean for faculty affairs and research. Violeta Chapin, clinical professor of law. Hiwot Covell, attorney with Sheridan Ross and chair of the Colorado Law Alumni Board.John Harrison, second-year law student. Taylor Hill, second-year law student.Kristine Jackson, assistant dean of admissions. Julia La Manna, attorney with Hogan Lovells and alumna.Suzette Malveaux, provost professor of civil rights law and director of The Byron R. White Center for the Study of American Constitutional Law. Helen Norton, professor and Ira C. Rothgerber Jr. Chair in Constitutional Law. Peter Sanders, assistant dean of advancement.Taylor Schad, third-year law student and law clerk at the Native American Rights Fund.Scott Skinner-Thompson, associate professor of law and affiliate faculty in LGBTQ Studies Program. Harry Surden, associate professor of law. Jane Thompson, senior instructor and associate director of faculty services at the Wise Law Library. Moore plans to name a new dean by May 2021.Categories:Deadlines & AnnouncementsCampus Communitylast_img read more

Balletto Vineyards Promotes Ian Bearup to Associate Winemaker

first_img TAGSBalletto VineyardsIan Bearuppeople Email Pinterest ReddIt Linkedin Home Industry News Releases Balletto Vineyards Promotes Ian Bearup to Associate WinemakerIndustry News ReleasesWine BusinessBalletto Vineyards Promotes Ian Bearup to Associate WinemakerBy Press Release – May 30, 2019 287 0 Facebook Share Twitter AdvertisementRussian River Valley Pinot Noir specialist promotes long-time winemaking team memberSanta Rosa, California (May 30, 2019) – Family-owned estate winery Balletto Vineyards, located in Sonoma County’s Russian River Valley AVA, has promoted Ian Bearup to associate winemaker. In this new role, Bearup will continue working closely with vice president and winemaker Anthony Beckman and play a key role in crafting Balletto Vineyards’ award-winning Pinot Noirs and Chardonnays. Bearup has worked at Balletto Vineyards for almost a decade and most recently was assistant winemaker.“The very first day I worked with Ian I knew I wanted him to be a mainstay on my winemaking team,” recalls Beckman. “He is such a rare breed of pure talent, intelligence and work ethic that it was impossible to let him go to any other winery. Ian is capable of making wine anywhere and we’re proud to have him on the Balletto Vineyards team.”Ian, who was raised in upstate New York, didn’t originally plan on a winemaking career. But after working his first harvest at Sonoma County’s St. Francis Winery in 2007, he was hooked. After working wine harvests in New Zealand, Oregon and several California wine regions, Ian started with Balletto Vineyards in August of 2010 as a lab intern. He quickly proved his skill set and work ethic, which earned him a promotion to assistant winemaker in fall 2012.“Ian is an integral part of our team and a big part of our family here at Balletto Vineyards,” remarked John Balletto, owner and founder of Balletto Vineyards. “Part of our philosophy is to identify, develop and promote excellence, in not just our wines, but in our employees. Ian is the perfect example of what we strive to do.”About Balletto VineyardsBalletto Vineyards is an estate winery in the famed Russian River Valley appellation of Sonoma County, California. Owned and operated by the Balletto family, Balletto Vineyards delivers honest and approachable estate wines meant to be enjoyed with family and friends. Owner John Balletto and his wife, Terri, started in the vegetable farming business, growing into the largest vegetable farm in Northern California. Seeing a bright future for wine grape growing in Russian River Valley, John and Terri transitioned to grape growing in 1995. In 2001, they created the first vintage of Balletto Vineyards estate wine from Russian River Valley. For more information, visit BallettoVineyards.com.Advertisement Previous articleChappellet Appoints David Francke Managing DirectorNext articleCatoctin Breeze Vineyard Wins 2019 Comptroller’s Cup with 2017 Estate Cabernet Franc Press Releaselast_img read more

COVID cases decline among homeless population

first_imgTo date, 44 people who were experiencing homelessness and two people who were working in shelters have passed away from COVID-19. Of the people who were experiencing homelessness who passed away, 21 were sheltered, 13 were unsheltered, and for 10 people who passed away, their sheltered status was unknown. There were no new deaths reported among people experiencing homelessness or shelter staff this week. Testing results are available for more than 2,737,000 individuals with 9% of all people testing positive.  This underscores the importance of ensuring that people experiencing homelessness are connected to support and interim housing, including access to health and substance use disorder services. Even before the pandemic, multiple studies have documented people experiencing homelessness have a mortality rate from three to eight times higher than those in the general population.  In reviewing L.A. County Coroner’s preliminary data, COVID-19 deaths do not appear to be the main driver of excess mortality among persons experiencing homelessness.  Public Health has seen an increase in drug overdoses among people experiencing homelessness. Drug overdoses accounted for 21% of deaths among persons experiencing homelessness in Los Angeles County from 2013-2018.  For the first 6 months of 2020, an estimated 40% of deaths among persons experiencing homelessness have been attributed to overdose. HomeBriefsCOVID cases decline among homeless population Oct. 07, 2020 at 5:00 amBriefsCovid-19HealthHomelessnessCOVID cases decline among homeless populationGuest Author8 months agoCOVID-19public healthPhoto by Kit Karzen. The Los Angeles County Department of Public Health (Public Health) has confirmed 30 new deaths and 990 new cases of confirmed COVID-19. To date, Public Health has identified 275,856 positive cases of COVID-19 across all areas of L.A. County, and a total of 6,681 deaths. The number of cases among persons experiencing homelessness has remained below what was predicted during the early stages of the pandemic. This may be, in part, because of the County’s early efforts to offer housing for people experiencing homelessness, including single-room facilities for the most at risk of serious illness, and for those needing to quarantine or isolate.  In addition, robust testing in shelters and a contact tracing approach tailored to people experiencing homelessness may have contributed to lower than expected cases. There are 685 confirmed cases currently hospitalized and 29% of these people are confirmed cases in the ICU. Santa Monica has reported 915 cases.  To date, Public Health has identified 1,846 cases among people experiencing homelessness. The weekly number of new cases among this group has declined significantly.  Cases among people experiencing homelessness peaked the week of July 7 at 138 new cases.  This week, there are 53 new cases among people experiencing homelessness.  This includes 36 cases from previous weeks that were newly identified and were included in the new case totals. Submitted by The Los Angeles County Public Health Department Tags :COVID-19public healthshare on Facebookshare on Twitteradd a commentSMC Emeritus Gallery to Host Online Opening Reception for Catherine Tirr Exhibition October 22Red Cross Partners with Panda Express to Support Disaster ReliefYou Might Also LikeBriefsLos Angeles Sheriff’s deputy accused of destroying evidence of 2019 assaultAssociated Press9 hours agoBriefsCalifornia State Treasurer Fiona Ma to Speak at Online Santa Monica College Commencement Ceremony June 25Guest Author9 hours agoBriefsNews“Righting Our Wrongs” performance on June 11Guest Author1 day agoBriefsNewsSEATTLE Feds plan to curtail West Coast salmon fishing to help orcasGuest Author1 day agoBriefsNewsBeach House Begins Community Re-Opening June 15Guest Author1 day agoBriefsNewsInput Invited for Marine Park Improvement ProjectsGuest Author1 day agolast_img read more

Donegal man charged in connection to Strokestown incident

first_img Google+ Important message for people attending LUH’s INR clinic DL Debate – 24/05/21 Twitter WhatsApp Arranmore progress and potential flagged as population grows Facebook Homepage BannerNews A Donegal man has appeared in court in Co. Roscommon charged with violent disorder at a house near Strokestown before Christmas.54 year old PJ Sweeney, whose address is given as High Cairn, Ramelton, was charged in connection to an attack which occurred in the wake of an eviction served by order of the High Court on a house in Falsk, near Strokestown in Co. Roscommon.Evidence of arrest, charge and caution was given at a special sitting of Roscommon District Court, to which the accused made no response.Mr Sweeney was refused bail and was remanded in custody, to appear at Harristown District Court in Castlerea, on Friday. Google+ Twitter Pinterestcenter_img Pinterest Previous article3-1 friendly win for Derry City over Cockhill CelticNext articleAnger after children’s playpark destroyed in Eglinton News Highland Donegal man charged in connection to Strokestown incident Facebook News, Sport and Obituaries on Monday May 24th By News Highland – January 13, 2019 Loganair’s new Derry – Liverpool air service takes off from CODA WhatsApp RELATED ARTICLESMORE FROM AUTHOR Nine til Noon Show – Listen back to Monday’s Programmelast_img read more